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miR-141-3p alleviates ulcerative colitis by targeting SUGT1 to inhibit colonic epithelial cell pyroptosis.
Yan R, Liang X, Hu J. Yan R, et al. Autoimmunity. 2023 Dec;56(1):2220988. doi: 10.1080/08916934.2023.2220988. Autoimmunity. 2023. PMID: 37317573 Free article.
In addition, miR-141-3p decreased the expression of pyroptosis-related proteins such as NLRP3, caspase-1, N-GSDMD, and the other proteins, as well as the release of IL-18 and IL-1beta inflammatory factors. ...Dual luciferase experiments confirmed that miR-141-3p could targ …
In addition, miR-141-3p decreased the expression of pyroptosis-related proteins such as NLRP3, caspase-1, N-GSDMD, and the other prot …
Analysis of inflammasomes and antiviral sensing components reveals decreased expression of NLRX1 in HIV-positive patients assuming efficient antiretroviral therapy.
Nasi M, De Biasi S, Bianchini E, Digaetano M, Pinti M, Gibellini L, Pecorini S, Carnevale G, Guaraldi G, Borghi V, Mussini C, Cossarizza A. Nasi M, et al. AIDS. 2015 Sep 24;29(15):1937-41. doi: 10.1097/QAD.0000000000000830. AIDS. 2015. PMID: 26237098
By RT-PCR, using peripheral blood mononuclear cells (PBMCs), we quantified the mRNA expression of 16 genes involved in inflammasome activation and regulation (AIM2, NAIP, PYCARD, CASP1, CASP5, NLRP6, NLRP1, NLRP3, TXNIP, BCL2, NLRC4, PANX1, P2RX7, IL-18, IL-1beta, SUGT1 …
By RT-PCR, using peripheral blood mononuclear cells (PBMCs), we quantified the mRNA expression of 16 genes involved in inflammasome activati …